Summary
The BIOCARD Study, at the Johns Hopkins University School of Medicine, is designed to identify biomarkers associated with progression from normal cognitive status to cognitive impairment or dementia, with a particular focus on Alzheimer's Disease. Participants are evaluated annually with cognitive testing, clinical examinations, and blood collection. Bi-annually, magnetic resonance imaging and cerebrospinal fluid are collected. Amyloid imaging (using PiB) is also collected.
About This Data Partner
The BIOCARD Study (officially entitled "Biomarkers of Cognitive Decline Among Normal Individuals: the BIOCARD cohort") is supported by a grant from the National Institute on Aging (NIA). The overarching goal of the BIOCARD Study is to identify biomarkers associated with progression from normal cognitive status to cognitive impairment or dementia, with a particular focus on Alzheimer's Disease. The study was initiated at NIMH in 1995. Investigators at the Johns Hopkins University School of Medicine began evaluating participants in 2009. The subjects are seen annually. At each annual visit there are assessments of medical, neurologic, psychiatric and cognitive status, and blood is collected. Bi-annually there is acquisition of MRI and CSF. PET-PiB and Tau-PET are also collected.
Additional Information
Principal Investigator(s)
Marilyn S. Albert
Data Available
Cognitive test scores, Clinical data, Consensus Diagnoses, Genetic data, Magnetic Resonance Imaging scans and measurements, Amyloid Imaging scan measurements (PET-PiB scans), Blood measurements, Cerebrospinal fluid values, Neuropathology data
The Global Alzheimer's Association Interactive Network