Summary
Japanese ADNI aims to establish imaging and biofluid markers that can predict and monitor the progression of changes in the brains of elderly participants with AD, mild cognitive impairment (MCI) or normal cognition, and eventually be used as a surrogate markers for the clinical trials of disease modifying drugs for AD. 3 year longitudinal data for 149 cognitively normal participants and 234 participants with MCI and 2 year longitudinal data for 154 participants with AD are available.
About This Data Partner
The data includes demographics, clinical, psychometric, imaging, biomarker and genetic data. The project was conducted in 38 clinical sites throughout Japan and the data is stored in Tokyo, Japan. The data partner, the University of Tokyo is the national academic institution which the principal investigator of J-ADNI belongs to.
Additional Information
Principal Investigator(s)
Takeshi Iwatsubo, MD
Contact Phone
+81-3-5841-3541
Data Available
Demographics, Clinical (including CDR, FAQ, GDS and NPI), Psychometry (MMSE, ADAS-cog, logical memory, clock drawing test, digit symbol substitution, category fluency, Boston naming test, trail making test), PiB-PET, BF227-PET, FDG-PET, structural MRI (FreeSurfer data), CSF biomarkers, APOE genotype